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Table 3 All patients: diagnostic performance of MSR and HSR of myocardial CTP

From: Myocardial CT perfusion imaging for the detection of obstructive coronary artery disease: multisegment reconstruction does not improve diagnostic performance

  All 93 patients
Per-patient level Per-territory level
Reconstruction/performance HSR MSR  p-value HSR MSR p-value
Area under the curvea 0.79 [0.69, 0.88] 0.65 [0.53, 0.78] 0.011 0.87 [0.83, 0.92] 0.71 [0.65, 0.78] < 0.001
Sensitivity 88 (51/58) [77, 95] 67 (39/58) [54, 79] 0.001 79 (68/86) [69, 87] 50 (43/86) [39, 61] < 0.001
Specificity 49 (17/35) [31, 66] 66 (23/35) [48, 81] 0.114 83 (171/206) [77, 88] 87 (179/206) [82, 91] 0.118
Positive predictive value 74 (51/69) [62, 84] 76 (39/51) [63, 87] 0.541 66 (68/103) [56, 75] 61 (43/70) [49, 73] 0.263
Negative predictive value 71 (17/24) [49, 87] 55 (23/42) [39, 70] 0.027 90 (171/189) [85, 94] 81 (179/222) [75, 86] < 0.001
  1. Reference: ≥ 50% diameter vessel stenosis detected in quantitative invasive coronary angiography. Data are the results of consensus reading of two readers. Unless otherwise stated, data are percentages, data in parentheses are raw data, and data in brackets are 95% confidence intervals. The 95% confidence intervals were estimated for unclustered data (see reference [31]). aData are the area under the curve and data in brackets are 95% confidence intervals. CTP Computed tomography perfusion, HSR Halfscan reconstruction, MSR Multisegment reconstruction