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Table 2 Characteristics of the 134 patients analysed in this study

From: Myocardial CT perfusion imaging for the detection of obstructive coronary artery disease: multisegment reconstruction does not improve diagnostic performance

Characteristic All patients (n = 134) Diagnostic performance comparison and radiation dose index group (n = 93)c Radiation dose control group (n = 41)c p-value
Age (years)a 65.7 (55.9–70.2) 62.9 (54.5–70.0) 67.1 (64.4–70.1) 0.013
Men 73 (98) 69 (64) 83 (34) 0.090
Body mass indexa, b 26.8 (25.2–30.0) 27.0 (25.4–30.4) 26.3 (24.7–29.3) 0.163
Dyslipidaemia 69 (93) 69 (64) 71 (29) 0.825
Arterial hypertension 80 (107) 81 (75) 78 (32) 0.730
Diabetes mellitus 27 (36) 24 (22) 34 (14) 0.207
Clinical presentation
 Typical angina 24 (32) 22 (20) 29 (12) 0.331
 Atypical angina 27 (36) 25 (23) 32 (13) 0.401
 Nonspecific chest pain 20 (27) 22 (20) 17 (7) 0.556
 No chest pain 29 (39) 32 (30) 22 (9) 0.226
Positive stress test
 Electrocardiography 7 (9) 6 (6) 7 (3) 0.494
 Echocardiography 14 (19) 11 (10) 22 (9) 0.087
 Magnetic resonance perfusion imaging 17 (23) 16 (15) 20 (8) 0.632
 Single-photon emission computed tomography 36 (48) 39 (36) 29 (12) 0.294
Pretest CAD status
 Prevalence of CAD     
  Suspected or no obstructive disease 29 (39) 27 (25) 34 (14) 0.394
  One-vessel disease 31 (42) 31 (29) 32 (13) 0.952
  Two-vessel disease 22 (29) 24 (22) 17 (7) 0.394
  Three-vessel disease 16 (22) 16 (15) 17 (7) 0.892
  Four-vessel disease 1 (2) 2 (2) 0 (0) 0.999
Stress CTP parameters
 Contrast medium dose (ml) a 60 (60–70) 60 (60–70) 60 (60–70) 0.130
 Heart rate (bpm) a 66.4 (61.5–74.5) 70.7 (64.9–76.4) 58.0 (53.3–64.1) 0.001
 2-segment MSR 63 (84) 90 (84) 0 (0) < 0.001
 3-segment MSR 7 (9) 10 (9) 0 (0) 0.057
 Per-segment temporal reconstruction window (ms) a 129.7 (102.8–175.0) 115.3 (96.8–132.5) 175 (175–175) < 0.001
  1. Data are percentages with numbers of patients in parentheses, unless otherwise stated. aData are medians with interquartile ranges in parentheses (data not normally distributed). bCalculated as \( \frac{\mathrm{weight}\ \mathrm{in}\ \mathrm{kg}}{{\left(\mathrm{height}\ \mathrm{in}\ \mathrm{m}\right)}^2} \). cSince a heart rate ≥ 65 bpm was the predefined cutoff for multisegment acquisition in the primary studies, the population for comparing the diagnostic performance of MSR and HSR of myocardial CTP consisted of 93 of 134 patients with multisegment acquisition of stress CTP allowing both MSR and HSR. The remaining 41 of 134 patients had single-segment acquisition due to heart rates < 65 bpm, and only HSR was possible. These patients served as a control group for interindividual radiation dose comparison (Fig. 1). bpm Beats per minute, CAD Coronary artery disease, CTP Computed tomography perfusion, HSR Halfscan reconstruction, MSR Multisegment reconstruction