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Table 1 Patient demography and oncological data of the investigated patients

From: Reversible occlusion of the pulmonary vasculature by transarterial embolisation with degradable starch microspheres: preclinical assessment in a human isolated lung perfusion model

Case

1

2

3

4

5

6

Age (years)

63

67

71

61

66

66

Sex

Male

Male

Female

Female

Female

Female

Emphysema

No

Yes

No

No

No

No

Smoker (packs/year)

Ex (35)

Yes (35)

Ex (20)

Ex (30)

Yes (28)

Yes (50)

FEV1 (%)

81

57

72

89

80

81

rTLC (%)

97

115

107

102

103

98

DLCO (%)

74,5

25,9

72,3

53,5

102,2

63,7

Surgical access

Thoracotomy

Thoracotomy

uVATS

Thoracotomy

Thoracotomy

Thoracotomy

Lobe

Right LL

Right LL

Right LL

Right LL

Right ML+LL

Right LL

Perfused segments

5

5

5

4 a

7

5

Histopathology

SCC

SCC

SCC

AC

SCC

SCC b

TNM staging and grading c

pT1b pN0 G3 L0 V0 R0

pT2a pN1 G3 L1 V0 R0

pT2a pN0 G3 L0 V1 R0

pT1b pN0 G2 L0 V0 R0

pT1c pN1a G2 L0 V1 R0

ypT0 ypN0 GX L0 V0 R0

Warm ischemia time (min)

40

60

18

46

20

12

Cold ischemia time (min)

310

347

194

159

230

292

Total ischemia time (min)

350

407

212

205

250

304

  1. AC Adeno carcinoma, DLCO Diffusion capacity of the lungs for carbon monoxide, Ex Ex-smoker, FEV1 Forced expiratory volume in one second, LL Lower lobe, PY Pack/year, rTLC Real total lung capacity, SCC Squamous cell carcinoma, uVATS Uniportal video-assisted thoracoscopic surgery
  2. aPatient 4 underwent a wedge resection before lobectomy; thus, the perfused segments were estimated at 4
  3. bPatient 6 had a neoadjuvant treatment with cisplatin/vinorelbine and 45 Gy of irradiation; initial tumour stage was cT2 cN2 cM0
  4. cAccording to the 8th UICC TNM edition (https://www.uicc.org/resources/tnm/publications-resources)