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Table 1 Patient demography and oncological data of the investigated patients

From: Reversible occlusion of the pulmonary vasculature by transarterial embolisation with degradable starch microspheres: preclinical assessment in a human isolated lung perfusion model

Case 1 2 3 4 5 6
Age (years) 63 67 71 61 66 66
Sex Male Male Female Female Female Female
Emphysema No Yes No No No No
Smoker (packs/year) Ex (35) Yes (35) Ex (20) Ex (30) Yes (28) Yes (50)
FEV1 (%) 81 57 72 89 80 81
rTLC (%) 97 115 107 102 103 98
DLCO (%) 74,5 25,9 72,3 53,5 102,2 63,7
Surgical access Thoracotomy Thoracotomy uVATS Thoracotomy Thoracotomy Thoracotomy
Lobe Right LL Right LL Right LL Right LL Right ML+LL Right LL
Perfused segments 5 5 5 4 a 7 5
Histopathology SCC SCC SCC AC SCC SCC b
TNM staging and grading c pT1b pN0 G3 L0 V0 R0 pT2a pN1 G3 L1 V0 R0 pT2a pN0 G3 L0 V1 R0 pT1b pN0 G2 L0 V0 R0 pT1c pN1a G2 L0 V1 R0 ypT0 ypN0 GX L0 V0 R0
Warm ischemia time (min) 40 60 18 46 20 12
Cold ischemia time (min) 310 347 194 159 230 292
Total ischemia time (min) 350 407 212 205 250 304
  1. AC Adeno carcinoma, DLCO Diffusion capacity of the lungs for carbon monoxide, Ex Ex-smoker, FEV1 Forced expiratory volume in one second, LL Lower lobe, PY Pack/year, rTLC Real total lung capacity, SCC Squamous cell carcinoma, uVATS Uniportal video-assisted thoracoscopic surgery
  2. aPatient 4 underwent a wedge resection before lobectomy; thus, the perfused segments were estimated at 4
  3. bPatient 6 had a neoadjuvant treatment with cisplatin/vinorelbine and 45 Gy of irradiation; initial tumour stage was cT2 cN2 cM0
  4. cAccording to the 8th UICC TNM edition (https://www.uicc.org/resources/tnm/publications-resources)