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Table 3 Summary of the correlation between features and grade group as well as the repeatability in peripheral zone cancer

From: DWI-related texture analysis for prostate cancer: differences in correlation with histological aggressiveness and data repeatability between peripheral and transition zones

Base image/features First/second Grade group Grade group 1, 2 vs. 3, 4, 5 ICC 95% CI Bland-Altman plot (%)
Spearman's ρ 95% CI p AUC of ROC Bias SD of bias 95% LOA
ADC (0, 1,000)
ADC 10% First -0.4027 -0.6725 to -0.03854 0.0273 0.732 0.773 0.580 to 0.885 -0.2016 21.15 -41.65 to 41.25
Second -0.4241 -0.6864 to -0.06427 0.0195 0.737
ADC 25% First -0.3638 -0.6467 to 0.007035 0.0481 0.705 0.825 0.667 to 0.912 0.06553 15.54 -30.40 to 30.53
Second -0.411 -0.6779 to -0.04843 0.0241 0.728
ADC (0, 1,500)
ADC 5% First -0.3738 -0.6534 to -0.004499 0.0419 0.705 0.817 0.654 to 0.908 -8.692 19.58 -47.08 to 29.69
Second -0.4389 -0.6959 to -0.08239 0.0152 0.759
ADC 10% First -0.418 -0.6824 to -0.05691 0.0215 0.737 0.829 0.674 to 0.915 -7.875 15.9 -39.04 to 23.29
Second -0.463 -0.7111 to -0.1123 0.01 0.763
ADC 25% First -0.4035 -0.673 to -0.03941 0.027 0.714 0.865 0.738 to 0.933 -5.203 11.99 -28.71 to 18.31
Second -0.3736 -0.6532 to -0.004216 0.042 0.71
ADC (100, 1,000)
ADC 10% First -0.4083 -0.6761 to -0.04522 0.0251 0.732 0.75 0.542 to 0.872 -6.843 21.59 -49.16 to 35.47
Second -0.5043 -0.7368 to -0.1652 0.0045 0.786
ADC 25% First -0.4103 -0.6774 to -0.04755 0.0243 0.723 0.786 0.601 to 0.892 -4.467 15.91 -35.66 to 26.73
Second -0.4555 -0.7064 to -0.1029 0.0114 0.754
ADC 50% First -0.3794 -0.6571 to -0.01101 0.0387 0.692 0.82 0.658 to 0.910 -3.982 11.12 -25.77 to 17.81
Second -0.4013 -0.6715 to -0.0368 0.028 0.714
ADC (100, 1,500)
ADC 5% First -0.3903 -0.6643 to -0.02385 0.033 0.719 0.816 0.651 to 0.907 -4.456 18.31 -40.35 to 31.44
Second -0.4142 -0.6799 to -0.05222 0.0229 0.746
ADC 10% First -0.4275 -0.6886 to -0.06841 0.0184 0.741 0.839 0.692 to 0.920 -6.85 12.82 -31.97 to 18.27
Second -0.4591 -0.7087 to -0.1074 0.0107 0.763
ADC 25% First -0.4528 -0.7047 to -0.09954 0.012 0.746 0.843 0.699 to 0.922 - 5.629 10.96 -27.10 to 15.85
Second -0.4039 -0.6733 to -0.03999 0.0268 0.732     
  1. 95% CI 95% confidence interval, 95% LOA 95% Limit of agreement, AUC Area under the curve, ICC Intraclass correlation coefficient, ROC Receiver operating characteristic, SD Standard deviation