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Table 1 Magnetic resonance sequences used for the relaxation times calculations

From: Quantification of H217O by 1H-MR imaging at 3 T: a feasibility study

Sequences Echo time (TE); repetition time (TR) Flip angle Acquisition matrix; voxel size (mm) SENSE acceleration factor; number of acquisitions
Three-dimensional T1-weighted gradient-echo with variable flip angle TE = 4.6 ms; TR = 14 ms 5 different (5°, 10°, 15°, 20° and 45°) 192 × 192 × 15; 1.88 × 1.88 × 5 2; 1
Two-dimensional T2*-weighted gradient-echo TR = 13; 12 TEs. Two different acquisitions with different echo time intervals (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 ms; and 15, 17.8, 20.6, 23.4, 26.2, 29, 31.8, 34.6, 37.4, 40.2, 43, 45.8 ms) 10° 96 × 96 × 13; 1.88 × 1.88 × 5 1.8; 1
Two-dimensional T2-weighted turbo spin-echo TR = 800; 8 TEs. Four different acquisitions with different echo time intervals (10, 20, 30, 40, 50, 60, 70, 80 ms; 20, 40, 60, 80, 100, 120, 140, 160 ms; 40, 80, 120, 160, 200, 240, 280, 320 ms; 50, 100, 150, 200, 250, 300, 350, 400 ms) 90° 96 × 96 × 1; 1.67 × 1.67 × 5 1; 1
  1. SENSE Sensitivity encoding parallel imaging method