Fig. 3

Apparent diffusion coefficient (ADC) in the contralateral region. Typical ADC maps of wild-type (WT) and aquaporin-4 knockout (AQP4-KO) mice (top and bottom, respectively), focused on the contralateral region (a). The ADC in the contralateral region has a range of 4–8 × 10⁻⁴ mm²/s. The plots show the mean ADC of each WT (blue) and AQP4-KO (red) mouse for each b-value range and Δ (b). The black bars correspond to the mean over animals. The results of the statistical analysis are shown in Table 2. The ADC maps and bar graphs for b = 4,000–6,000, and 6,000–8,000 s/mm² are excluded because of low signal-to-noise ratio (see Fig. S3)