Fig. 2

Apparent diffusion coefficient (ADC) in the ischemic region. Typical ADC maps of wild-type (WT) (top) and aquaporin-4 knockout (AQP4-KO) mice (top and bottom, respectively) focused on the ipsilateral region at Δ = 70 ms (a). The ADC in the ischemic region has a range of 0–5 × 10⁻⁴ mm²/s. The plots show the mean ADC of each WT (blue) and AQP4-KO (red) mouse for each b-value range and Δ (b). The black bars correspond to the mean over animals. The results of the statistical analysis are shown in Table 1