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Table 1 Net quantitative enhancement and per-region of interest (per-ROI) average quantitative enhancement for 27 patients with histologically confirmed glioblastoma from the TRUTH study [18]

From: The TRUTH confirmed: validation of an intraindividual comparison of gadobutrol and gadoteridol for imaging of glioblastoma using quantitative enhancement analysis

Patient

Net quantitative enhancement

Per-ROI average quantitative enhancement

Gadoteridol

Gadobutrol

Difference

Gadoteridol

Gadobutrol

Difference

1

2,660.6

2,355.5

305.1

0.096

0.085

0.011

2

225.3

196.1

29.1

0.040

0.034

0.005

3

7,421.5

6,814.4

607.1

0.139

0.128

0.011

4

1,829.6

1,533.0

296.6

0.113

0.095

0.018

5

736.3

949.3

-213.0

0.163

0.210

− 0.047

6

1,836.3

1,635.1

201.1

0.211

0.188

0.023

7

2,306.0

2,816.1

-510.1

0.130

0.159

− 0.029

8

711.3

695.5

15.8

0.176

0.172

0.004

9

2,445.9

2,225.5

220.4

0.093

0.084

0.008

10

3,755.9

3,356.3

399.6

0.380

0.339

0.040

11

9,759.5

9,814.0

-54.5

0.217

0.218

− 0.001

12

596.4

534.8

61.6

0.089

0.079

0.009

13

2,326.9

2,505.6

-178.7

0.184

0.198

− 0.014

14

308.1

317.2

-9.1

0.065

0.067

− 0.002

15

1,255.6

1,082.3

173.3

0.102

0.088

0.014

16

280.5

226.9

53.6

0.039

0.031

0.007

17

2,353.9

2,640.1

-286.2

0.182

0.205

− 0.022

18

277.3

248.1

29.2

0.187

0.167

0.020

19

364.5

304.8

59.8

0.072

0.060

0.012

20

13,009.7

1,5861.3

-2851.6

0.159

0.194

− 0.035

21

142.0

129.9

12.1

0.107

0.098

0.009

22

1,247.2

873.2

374.0

0.172

0.120

0.052

23

2119.5

2,103.0

16.6

0.190

0.189

0.001

24

230.1

164.5

65.6

0.041

0.029

0.012

25

1,339.9

1,539.6

-199.7

0.148

0.170

− 0.022

26

1,453.5

1,402.2

51.3

0.060

0.058

0.002

27

1,307.5

634.4

673.1

0.057

0.028

0.029

Mean ± SD

2,307.4 ± 3,045.4

2,331.8 ± 3,445.4

-24.4 ± 620.8

0.134 ± 0.074

0.129 ± 0.076

0.004 ± 0.022

p-value*

  

0.840

  

0.313

  1. Positive difference values for individual patients indicate greater enhancement for gadoteridol; negative values indicate greater enhancement for gadobutrol. *p-value is from paired t-test for difference (gadoteridol minus gadobutrol)