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European Radiology Experimental
Fig. 9 | European Radiology Experimental

Fig. 9

From: The TRUTH confirmed: validation of an intraindividual comparison of gadobutrol and gadoteridol for imaging of glioblastoma using quantitative enhancement analysis

Fig. 9

74-year-old woman with glioblastoma in the right centrum semiovale. Conventional T1-weighted SE contrast-enhanced images for the first exam with gadoteridol (a) and the second exam with gadobutrol (b) and the QE change map (c) where colour indicates regions differing in enhancement between the two exams. Scatter charts (T1-weighted contrast-enhanced versus unenhanced) of enhancing voxel regions of interest reveals the patterns of enhancement for gadoteridol (d) and gadobutrol (e). The net QE was +711.26 for gadoteridol (a, d) and +695.47 for gadobutrol (b, e). The gadoteridol minus gadobutrol difference (15.79, 2.22%) was not significant, and the 90% confidence interval for the mean of the differences fell entirely within the equivalence zone indicating equivalence for the two contrast agents, as demonstrated in the comparative scatter chart (f)

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