Prognostic value of DCE-CT-derived blood volume and flow compared to core biopsy microvessel density in patients with metastatic renal cell carcinoma

European Radiology Experimental

Table 3 Correlations between DCE-CT parameters, HU, and CD34-index at baseline

	All patients (n = 25) SCC (p-value)		Synchronous mRCC (n = 19) SCC (p-value)		Metachronous mRCC (n = 6) SCC (p-value)
	CD34-index_T	CD34-index_TN	CD34-index_T	CD34-index_TN	CD34-index_T	CD34-index_TN
BV_deconv	0.23 (0.275)	0.21 (0.317)	0.20 (0.416)	0.19 (0.429)	0.14 (0.787)	0.14 (0.787)
BV_Patlak	0.20 (0.351)	0.17 (0.417)	0.23 (0.336)	0.22 (0.367)	0.09 (0.872)	0.09 (0.872)
BF_deconv	0.26 (0.207)	0.22 (0.289)	0.27 (0.273)	0.23 (0.344)	0.14 (0.787)	0.14 (0.787)
HU	0.20 (0.351)	0.22 (0.285)	0.12 (0.624)	0.18 (0.466)	0.31 (0.544)	0.31 (0.544)

BV_deconv Blood volume (deconvolution), BV_Patlak Blood volume (Patlak), BF_deconv Blood flow (deconvolution), CD34-index_TN CD34-index in the tumour necrosis outline, CD34-index_T CD34-index in the tumour outline, DCE-CT Dynamic contrast-enhanced computed tomography, HU Hounsfield units, mRCC Metastatic renal cell carcinoma, SCC Spearman correlation coefficient (rho)