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Table 3 Virtual non-calcium computed tomography potential to visualize non-traumatic bone marrow edema on dual-energy scans of spine and pelvic girdle

From: Virtual non-calcium dual-energy CT: clinical applications

Authors, year [reference]

DECT platform

Number of patients

Qualitative analysis (sensitivity, specificity, accuracy)

Quantitative analysis cutoff (sensitivity, specificity, accuracy)

Reference standard

Disorder

Anatomical site

Shinohara et al., 2020 [61]

DSCT

53

NA

NA

MRI

Disc degeneration

Spine

Foti et al., 2020 [74]

DSCT

59

95%, 86%, 93%

NA

MRI

Sacroiliitis

Hip

Chen et al., 2020 [71]

DSCT

40

81%, 94%, NA

-44 HU (76%, 91%, NA)

MRI

Sacroiliitis

Hip

Gruggeberger et al., 2020 [73]

DSCT

47

93%, 94%, NA

-35 HU (94%, 83%, NA)

MRI

Sacroiliitis

Hip

Abdullayev et al., 2019 [56]

DLCT

21

85%, 84%, 84%

NA

MRI

Vertebral metastases

Spine

Booz et al., 2019 [34]

DSCT

41

91%, 92%, 94%

NA

MRI

Disc herniation

Spine

Wu et al., 2019 [70]

DSCT

47

93%, 94%, 92%

-33 HU (90%, 83%, 83%)

MRI

Sacroiliitis Spondylarthritis

Spine/Hip

Kosmala et al., 2018 [12]

DSCT

53

NA

-36 HU (100%, 97%, 99%)

MRI

Multiple myeloma

Spine

Kosmala et al., 2018 [66]

DSCT

34

91%, 91%, 91%

-45 HU (93%, 92%, 93%)

MRI

Multiple Myeloma

Spine

  1. DECT Dual-energy computed tomography, DLCT Dual-layer computed tomography, DSCT Dual-source computed tomography, HU Hounsfield units, NA Not available, MRI Magnetic resonance imaging