Skip to main content

Table 4 Material density parameters of malignant and benign nodules on spectral computed tomography

From: Material decomposition using iodine quantification on spectral CT for characterising nodules in the cirrhotic liver: a retrospective study

MD parameters Malignant (HCC and indeterminate) 147 Benign (regenerative) 183 p value
On HAP
 ICDnodule (mg/mL) 19 (16–25) 9 (4–15) < 0.001
 LNR 2.8 (1.8–5.5) 0.8 ( 0.5–1.8) < 0.001
 NIC (mg/mL) 0.2 (0.1–0.2) 0.1 (0.04–0.1) < 0.001
 ICDliver (mg/mL) 6 (3–11) 8 (4–12) 0.002
On PVP
 ICDnodule (mg/mL) 10 (6–14) 13 (8–19) 0.004
 LNR 0.6 (0.4– 0.8) 0.6 (0.4–0.8) 0.869
 NIC (mg/mL) 0.2 (0.1–0.4) 0.3 (0.2–0.5) 0.003
 ICDliver (mg/mL) 16 (12–23) 18 (14–27) 0.007
Difference between HAP and PVP
 ΔICDnodule (mg/mL) Mean ± SD 8.3±11.2 -2.9 ± 9.5 < 0.001
  1. All MD values are presented as median (interquartile range)
  2. HAP Hepatic arterial phase, ICD Iodine concentration density, LNR Lesion-to-normal liver iodine density (LNR = ICD lesion/ICD normal liver), MD Material density of iodine, NIC Normalised iodine concentration (NIC = ratio of ICDnodule/ICDaorta), PVP Portal venous phase, SD Standard deviation, ΔICD Delta iodine concentration (ΔICD = ICDnodule HAP minus ICDnodule PVP)