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European Radiology Experimental
Fig. 6 | European Radiology Experimental

Fig. 6

From: Material decomposition using iodine quantification on spectral CT for characterising nodules in the cirrhotic liver: a retrospective study

Fig. 6

Spectral computed tomography-based material density (MD) map (iodine only image) and scatter plots with histopathological confirmation of an indeterminate nodule. a Axial MD map on HAP depicting indeterminate nodule with ROI (blue circle) placed at its centre (blue arrow), ROI (red circle) placed on the background liver parenchyma (orange arrow) and ROI (green circle) within the aorta at the same level (green arrow). b Scatter plot demonstrating ICDnodule HAP for nodule (blue arrow) more than the background liver ICDliver HAP (orange arrow) and less than ICDaorta (green arrow) as reference. c Histopathology confirmation of nodule, showing features of high-grade dysplasia. d Axial MD map acquired on PVP showing ROI (red circle) placed in the centre of the nodule (blue arrow), ROI (blue circle) on the liver parenchyma (orange arrow), and aorta (green circle) at the same level (green arrow). e Scatter plot demonstrating ICDnodule PVP (blue arrow) persistently higher than ICDliver PVP (orange arrow). f Immunohistochemistry slide showing CD34-positive foci (black bold arrow) in the nodule depicting dysplasia

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