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Table 4 Diagnostic performance for axillary ultrasonography and quantitative dual-layer spectral CT parameters for differentiating metastatic and non-metastatic axillary lymph nodes

From: Breast cancer: comparison of quantitative dual-layer spectral CT and axillary ultrasonography for preoperative diagnosis of metastatic axillary lymph nodes

  Cutoff AUC Sensitivity Specificity PPV NPV
Axillary ultrasound   0.88 0.75 1.00 1.00 0.67
Iodine density (mg/mL) 1.5 0.80 0.79 0.73 0.83 0.62
Spectral slope 0.82 0.83 0.79 0.83 0.90 0.63
Z effective 183 0.83 0.79 0.83 0.90 0.67
Conventional CT HU 53 0.79 0.58 0.92 0.93 0.52
VNC (HU) 18 0.78 0.79 0.67 0.83 0.62
Δ contrast enhancement (HU) 17 0.87 0.79 0.92 0.95 0.69
  1. CT Computed tomography, VNC Virtual non-contrast. AUC Area under the curve, NPV Negative predictive value, PPV Positive predictive value