Patient number/male or female | Additional clinical information | Current management | Position tip colonic catheter (as shown on abdominal x-ray) | Colonic manometry channels visualised on cine-MRI | Number of HAPCs visualised on manometry in the descending colon | Results of colonic manometry |
---|---|---|---|---|---|---|
1/F | Concomitant symptoms of abdominal pain, nausea and depression | Treated with daily caecostomy flushes with saline and polyethylene glycol | Sigmoid colon | 3-6 | 0 | Abnormal colonic motility with lack of HAPCs in response to the administration of bisacodyl |
2/F | Concomitant symptoms of gastroesophageal reflux disease | Treated with daily caecostomy flushes with saline, bisacodyl and polyethylene glycol | Distal descending colon | 6–8 | 0 | Normal colonic motility in the colon proximal to the splenic flexure; abnormal motility in the descending colon with lack of HAPCs in response to the administration of bisacodyl |
3/M | Known with obesity | Treated with high dosage of daily lactulose, polyethylene glycol and bisacodyl | Hepatic flexure | 5–7 | 3 | Normal colonic motility |
4/F | Treated with daily caecostomy flushes with saline and bisacodyl | Rectosigmoid colon | 4–6 | 4 | Normal colonic motility | |
5/M | Known with obesity | Weekly cleanout with high dose polyethylene glycol and daily bisacodyl. | Cecum | 6–8 | 4 | Normal colonic motility |
6/M | Known with attention deficit/hyperactivity disorder | Daily polyethylene glycol | Hepatic flexure | 8 | 0 | Abnormal colonic motility with lack of HAPCs in response to the administration of bisacodyl |