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Table 2 Results for the deep learning classifier and human readings of study datasets

From: Machine learning applied on chest x-ray can aid in the diagnosis of COVID-19: a first experience from Lombardy, Italy

COVID-19 positive versus negative

Classifier validation (cross-validation)

 

Positive (n)

Negative (n)

Assigned positive

195

46

Assigned negative

55

204

 

Sensitivity

Specificity

 

0.78* (0.74–0.81)

0.82* (0.78–0.85)

 

LR+

LR-

 

4.24* (3.24–5.55)

0.27* (0.21–0.34)

Classifier independent testing

 

Positive (n)

Negative (n)

Assigned positive

59

7

Assigned negative

15

29

 

Sensitivity

Specificity

 

0.80* (0.72–0.86)

0.81* (0.73–0.87)

 

LR+

LR-

 

4.10* (2.09–8.05)

0.25* (0.16–0.41)

Human independent testing (Reader 1)

 

Positive (n)

Negative (n)

Assigned positive

47

8

Assigned negative

27

28

 

Sensitivity

Specificity

 

0.64 (0.52–0.74)

0.78 (0.61–0.90)

 

LR+

LR-

 

2.86 (1.51–5.39)

0.47 (0.33–0.66)

Human independent testing (Reader 2)

Assigned positive

47

5

Assigned negative

27

31

 

Sensitivity

Specificity

 

0.64 (0.52–0.74)

0.86 (0.71–0.95)

 

LR+

LR-

 

4.57 (1.99–10.50)

0.42 (0.31–0.59)

  1. Data are presented as value and 95% confidence interval. *p < 0.005. COVID-19 Coronavirus disease 2019, LR+ Positive likelihood ratio, LR- Negative likelihood ratio