Skip to main content
European Radiology Experimental
Fig. 3 | European Radiology Experimental

Fig. 3

From: A novel roadmap connecting the 1H-MRS total choline resonance to all hallmarks of cancer following targeted therapy

Fig. 3

Pro-survival ER-phagy and macroautophagy degradation of cellular components in a vacuole to maintain cellular homeostasis. ER-phagy packages excessive ER abundance in ER-whorls (concentric blue circles) and degrades them within an intracellular membranous vacuole, the lysosome. Macroautophagy engulfs cytoplasmic, misfolded proteins (small, grey circles), and non-functioning, aged intracellular membranes (blue ovals) and degrades them within the lysosome. To maintain cellular homeostasis, the degraded products are recycled (not shown). ER, Endoplasmic reticulum. Reprinted with permission from Schuck et al. [38]

Back to article page