Fig. 2

A 49-year-old female with invasive lobular carcinoma of the right breast with biopsy proven right axillary metastatic lymphadenopathy. A Tumark x-shaped marker was placed at site of axillary lymph node biopsy. a–d Initial staging magnetic resonance imaging (MRI) 2 weeks after lymph node marker placement. The marker is seen with high confidence on the T2-weighted water-only fast spin-echo image (a), the unenhanced fat-suppressed three-dimensional T1-weighted spoiled gradient-recalled image (c), and the first contrast-enhanced fat-suppressed three-dimensional T1-weighted spoiled gradient-recalled image (d), while it is seen with low confidence on the T2-weigheted fat-only fast spin-echo image (b). In the follow-up of neoadjuvant therapy, MRI was performed 6 months after biopsy marker placement. The marker is seen with low confidence on all images: T2-weighted water-only fast spin-echo image (e), T2-weighted fat-only fast spin-echo image (f), unenhanced fat-suppressed three-dimensional T1-weighted spoiled gradient-recalled image (g), and first contrast-enhanced fat-suppressed three-dimensional T1-weighted spoiled gradient-recalled image (h), with poor visualization attributed to the decreased size of lymph node cortical thickness