Table 5 Design and realisation of brain perfusion phantoms for quantitative perfusion imaging (PI)
From: Quantitative imaging: systematic review of perfusion/flow phantoms
1st author, year [reference] | Perfusion measure(s) | Phantom performance | Q |
|---|---|---|---|
Direct comparison with Q | |||
Klotz, 1999 [29] | BF | r = 0.990 | 50–140 mL/min |
Wang, 2010 [27] | BF | r > 0.834 | 45–180 mL/min |
Mathys, 2012 [31] | BF | r = 0.995 | 200–600 mL/min |
Peladeau-Pigeon, 2013 [12] | BF | r = 0.992 | 210–450 mL/min |
Ohno, 2017 [33] | BF | r > 0.90 | 240–480 mL/min |
Ziemer, 2015 [40] | BF | r = 0.98 | 0.96–2.49 mL/g/min |
O’Doherty, 2017 [36] | BF | r = 0.99 | 1–5 mL/g/min |
Andersen, 2000 [9] | BF | ε ≈ 0.015 ± 0.03 cm/s ε ≈ 0.001 ± 0.03 cm/s | 0.015 ± 0.002 cm/s 0.570 ± 0.003 cm/s |
Ressner, 2006 [39] | BF | ε > 40% ε < 20% | 1–3 cm/s 5–7 cm/s |
Zarinabad, 2012 [35] | BF | ε = 0.007 ± 0.002 mL/g/min ε = 0.23 ± 0.26 ml/g/min | 0.5 mL/g/min 5 mL/g/min |
Zarinabad, 2014 [34] | BF | ε < 0.03 mL/g/min ε < 0.05 ml/g/min | 2.5–5 mL/g/min 1–2.5 mL/g/min |
Suzuki, 2017 [25] | BF | ε ≈ 0.0589 ± 0.0108 mL/g/min | 0.1684 mL/g/min |
Hashimoto, 2018 [24] | BF | ε ≈ 0.0446 ± 0.0130 mL/g/min | 0.1684 mL/g/min |
Ebrahimi, 2019 [32] | BF | BF/Q > 0.6 | 0.12–1.2 mL/min |
Indirect comparison with Q | |||
Veltmann, 2002 [17] | rkin | r > 0.984, χ2 < 0.019 | 10–45 mL/min |
Chai, 2002 [20] | ∆SI ratio | r = 0.995 | 50–300 mL/min |
Cangür, 2004 [28] | TTP PSI AUC PG FWHM | r = -0.964 r = 0.683 r = 0.668 r = 0.907 r = -0.63 | 1.8–21.6 mL/min |
Myer-Wiethe, 2005 [16] | ∆SI | r = 0.99 | 4.5–36 mL/min |
Lee, 2016 [19] | fp | r > 0.838 | 1–3 mL/min |
O’Doherty, 2017 [36] | SI | r = 0.99 r = 0.99 | 1–5 mL/g/min (MRI) 1.2–5.1 mL/g/min (MRI vs PET) |
Kim, 2016 [14] | AUC | Efficiency <50% | 0.1–2.0 mL/min |
Claassen, 2001 [30] | AUC, PSI, MTT | No clear correlation with Q | |