Multiparametric quantitative and texture 18F-FDG PET/CT analysis for primary malignant tumour grade differentiation

European Radiology Experimental

Table 1 Stable radiomic parameters, independent from segmentation technique

	GLCM homogeneity	Energy	Sphericity
Absolute values in different segmentation techniques
SUVmax 2.5 threshold	0.37 ± 0.09	0.08 (0.06–0.12)	1.03 ± 0.05
Liver pool fixed threshold	0.38 ± 0.09	0.08 (0.06–0.12)	1.03 ± 0.04
41% SUVmax threshold	0.37 ± 0.08	0.09 (0.07–0.13)	1.04 ± 0.06
ITK-SNAP segmentation	0.37 ± 0.09	0.08 (0.06–0.13)	1.04 ± 0.05
p values for hypothesis of significant difference
2.5 versus liver	0.582	0.632	0.844
2.5 versus ITK-SNAP	0.788	0.954	0.541
2.5 versus 41%	0.968	0.344	0.534
Liver versus 41%	0.554	0.122	0.633
Liver versus ITK-SNAP	0.423	0.596	0.653
41% versus ITK-SNAP	0.819	0.303	0.932

Data are presented as mean ± standard deviation or median with interquartile range in parentheses
GLCM Grey level co-occurrence matrix, SUV Standardised uptake value