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Table 1 Demographic and imaging characteristics of the 253 patients in the internal dataset as well as their effects on liver overlap score

From: Fully automated convolutional neural network-based affine algorithm improves liver registration and lesion co-localization on hepatobiliary phase T1-weighted MR images

 

Demographic summary

Univariate analysis

Multivariate analysis

Stratum

Number of image pairs

Number of patients

Coefficient

95% CI

p

Coefficient

95% CI

p

Overall

2,225

253

0.86

[0.85, 0.87]

< 0.001

   

Age* (years)

58.38 ± 12.37 (38.60–77)

       

 < 45 (intercept)

260

33

0.89

[0.85, 0.92]

< 0.001

/

/

/

 45–64

1,211

142

− 0.02

[− 0.06, 0.02]

0.34

− 0.01

[− 0.04, 0.02]

0.56

 > 65

754

78

− 0.05

[− 0.09, − 0.01]

0.02

− 0.04

[− 0.07, 0.00]

0.06

Sex

        

 M (intercept)

1,062

108

0.87

[0.86, 0.89]

< 0.001

/

/

/

 F

1,163

145

− 0.03

[− 0.05, 0.00]

0.02

− 0.03

[− 0.05, − 0.01]

0.01

BMI* (kg/m2)

20.06 ± 5.99 (20.65–39.53)

       

 < 24.9 (intercept)

571

62

0.83

[0.81, 0.86]

< 0.001

   

 25–30

792

91

+ 0.03

[− 0.00, 0.06]

0.05

   

 > 30

842

94

+ 0.04

[0.01, 0.07]

0.01

   

Etiology

        

 Hepatitis B (intercept)

466

37

0.85

[0.82, 0.89]

< 0.001

   

 Hepatitis C

1,042

108

+ 0.01

[− 0.02, 0.05]

0.50

   

 Alcohol

164

33

− 0.01

[− 0.06, 0.04]

0.63

   

 Nonalcoholic fatty liver disease

276

35

+ 0.02

[− 0.02, 0.07]

0.39

   

 Autoimmune hepatitis

98

11

+ 0.03

[− 0.03, 0.10]

0.34

   

 Other

179

29

+ 0.00

[− 0.05, 0.05]

0.93

   

Time between series* (days)

324.72 ± 407.73 (0–1,255)

       

 Same day (intercept)

674

196

0.9

[0.89, 0.92]

< 0.001

/

/

/

 0–1 year

823

135

− 0.05

[− 0.06, − 0.04]

< 0.001

− 0.03

[− 0.04, − 0.02]

< 0.001

 1–2 years

469

93

− 0.08

[− 0.09, − 0.07]

< 0.001

− 0.05

[− 0.07, − 0.03]

< 0.001

 > 2 years

259

29

− 0.10

[− 0.12, − 0.08]

< 0.001

− 0.08

[− 0.10, − 0.06]

< 0.001

Artifacts

        

 No artifacts (intercept)

1,278

185

0.86

[0.85, 0.88]

< 0.001

   

 One image

597

105

− 0.00

[− 0.02, 0.01]

0.68

   

 Both images

350

65

− 0.01

[− 0.02, 0.01]

0.55

   

HBP contrast uptake adequacy

        

 Both adequate (intercept)

1,435

193

0.87

[0.86, 0.88]

< 0.001

/

/

/

 One adequate, one suboptimal

350

54

− 0.02

[− 0.03, − 0.01]

0.01

− 0.02

[− 0.03, 0.00]

0.01

 Both suboptimal

340

62

+ 0.02

[− 0.01, 0.04]

0.15

+ 0.00

[− 0.02, 0.02]

0.96

 Missing

100

16

/

/

/

/

/

/

Voxel volume difference* (mm3)

0.76 ± 1.52 (0–3.02)

       

 0 (intercept)

746

186

0.90

[0.89, 0.92]

< 0.001

/

/

/

 0–1

1,064

141

− 0.06

[− 0.07, − 0.05]

< 0.001

− 0.02

[− 0.03, − 0.01]

< 0.001

 > 1

402

86

− 0.09

[− 0.10, − 0.07]

< 0.001

− 0.05

[− 0.06, − 0.03]

< 0.001

Slice thickness* (mm)

4.53 ± 0.73 (3.00–6.00)

       

Pixel spacing* (mm)

0.82 ± 0.15 (0.70–0.94)

       
  1. BMI body mass index, HBP hepatobiliary phase
  2. * Mean +/- standard deviation; 5th and 95th percentiles in parentheses