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Table 2 Diagnostic performance of the two different methods for computing tumour-to-nipple-areola complex distance at different cut-off values

From: Nipple-sparing mastectomy: external validation of a three-dimensional automated method to predict nipple occult tumour involvement on preoperative breast MRI

ParametersAutomaticManualp value
Best (≤ 30 mm)≤ 5 mm≤ 10 mm≤ 20 mmBest (≤ 21 mm)≤ 5 mm≤ 10 mm≤ 20 mm
Sensitivity (%)78.38.726.134.873.943.543.573.90.537
Specificity (%)71.4100.0100.085.761.295.985.761.20.197
PPV (%)56.3100.100.053.347.283.358.847.20.276
NPV (%)87.570.074.373.783.378.376.483.30.477
Accuracy (%)73.670.876.469.565.379.272.265.30.281
  1. PPV positive predictive value, NPV negative predictive value