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Table 5 Changes in perfusion parameters, RECIST-1.1 diameter, and tumour volume in epidermoid carcinomas (n = 16)

From: Evaluation of response to conventional chemotherapy and radiotherapy by perfusion computed tomography in non-small cell lung cancer (NSCLC)

 

Partial response (n = 10)

Stable disease (n = 6)

Baseline

Control

p value

Baseline

Control

p value

Blood flow

(mL/100 mL/min)

176.1 ± 76.1

186.5 ± 106.4

0.775

234.9 ± 97.5

165.8 ± 108.7

0.010

Blood volume (mL/100 mL)

8.6 ± 3.3

5.9 ± 2.6

0.007

6.4 ± 2.8

5.2 ± 3.4

0.269

Permeability (mL/100 mL/min)

15.9 ± 6.9

11.1 ± 7.0

0.062

16.5 ± 11.5

6.7 ± 4.1

0.036

Mean transit time (s)

7.5 ± 3.6

5.3 ± 2.7

0.018

3.6 ± 1.7

5.3 ± 2.9

0.267

RECIST-1.1 diameter (mm)

54.5 ± 21.4

35.7 ± 15.7

0.002

62.5 ± 24.3

59.8 ± 23.9

0.082

Tumour volume (cc)

142.5 ± 171.8

56.1 ± 62.6

0.038

57.0 ± 4.6

22.5 ± 18.9

0.021

  1. RECIST Response evaluation criteria in solid tumours
  2. Significant p values are in bold