Skip to main content

Table 4 Changes in perfusion parameters, RECIST-1.1 diameter, and tumour volume in adenocarcinomas (n = 28)

From: Evaluation of response to conventional chemotherapy and radiotherapy by perfusion computed tomography in non-small cell lung cancer (NSCLC)

 

Partial response (n = 16)

Stable disease (n = 9)

Progressive disease (n = 3)

Baseline

Control

p value

Baseline

Control

p value

Baseline

Control

p value

Blood flow (mL/100 mL/min)

157.7 ± 87.6

139.9 ± 85.0

0.467

240.3 ± 274.0

192.1 ± 115.8

0.639

171.7 ± 146.2

170.4 ± 130.3

0.968

Blood volume (mL/100 mL)

7.5 ± 3.3

6.8 ± 3.0

0.397

9.0 ± 4.9

7.9 ± 2.8

0.572

7.3 ± 2.8

7.3 ± 4.8

0.975

Permeability (mL/100 mL/min)

15.3 ± 5.6

15.1 ± 7.7

0.913

20.2 ± 13.9

16.6 ± 6.1

0.491

18.3 ± 6.5

17.7 ± 9.6

0.809

Mean transit time (s)

6.7 ± 3.25

6.4 ± 2.3

0.710

6.3 ± 1.6

5.8 ± 2.0

0.350

7.8 ± 3.5

7.0 ± 3.6

0.465

RECIST-1.1 diameter (mm)

58.1 ± 25.3

41.4 ± 19.3

0.00

54.2 ± 25.0

51 ± 24.92

0.041

58.7 ± 20.4

65.0 ± 26.2

0.210

Tumour volume (cc)

99.6 ± 163.9

35.7 ± 62.9

0.051

125.0 ± 168.4

96.6 ± 150.0

0.137

93.3 ± 73.4

126.7 ± 97.6

0.145

  1. Significant p values are in bold
  2. RECIST Response evaluation criteria in solid tumours