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Table 4 Changes in perfusion parameters, RECIST-1.1 diameter, and tumour volume in adenocarcinomas (n = 28)

From: Evaluation of response to conventional chemotherapy and radiotherapy by perfusion computed tomography in non-small cell lung cancer (NSCLC)

  Partial response (n = 16) Stable disease (n = 9) Progressive disease (n = 3)
Baseline Control p value Baseline Control p value Baseline Control p value
Blood flow (mL/100 mL/min) 157.7 ± 87.6 139.9 ± 85.0 0.467 240.3 ± 274.0 192.1 ± 115.8 0.639 171.7 ± 146.2 170.4 ± 130.3 0.968
Blood volume (mL/100 mL) 7.5 ± 3.3 6.8 ± 3.0 0.397 9.0 ± 4.9 7.9 ± 2.8 0.572 7.3 ± 2.8 7.3 ± 4.8 0.975
Permeability (mL/100 mL/min) 15.3 ± 5.6 15.1 ± 7.7 0.913 20.2 ± 13.9 16.6 ± 6.1 0.491 18.3 ± 6.5 17.7 ± 9.6 0.809
Mean transit time (s) 6.7 ± 3.25 6.4 ± 2.3 0.710 6.3 ± 1.6 5.8 ± 2.0 0.350 7.8 ± 3.5 7.0 ± 3.6 0.465
RECIST-1.1 diameter (mm) 58.1 ± 25.3 41.4 ± 19.3 0.00 54.2 ± 25.0 51 ± 24.92 0.041 58.7 ± 20.4 65.0 ± 26.2 0.210
Tumour volume (cc) 99.6 ± 163.9 35.7 ± 62.9 0.051 125.0 ± 168.4 96.6 ± 150.0 0.137 93.3 ± 73.4 126.7 ± 97.6 0.145
  1. Significant p values are in bold
  2. RECIST Response evaluation criteria in solid tumours