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European Radiology Experimental
Fig. 2 | European Radiology Experimental

Fig. 2

From: Quantitative DWI predicts event-free survival in children with neuroblastic tumours: preliminary findings from a retrospective cohort study

Fig. 2

Baseline MRI of a 5-week-old boy with neuroblastoma of the right adrenal gland and suspected multiple liver metastases shown on T2-weighted image (a), DWI with b = 800 s/mm2 (b), and ADC map (c). To demonstrate the large region of interest (ROI) technique used in our study for ADC quantification, d presents a magnification of c with a solid black line as overlay marking the free-hand ROI drawn along the tumour margins. Mean ADC of the tumour was measured as 0.883 × 10−3 mm2/s, and the patient did not suffer a tumour relapse. Three additional small circular ROIs yielded ADC values from 0.778 to 1.107 × 10−3 mm2/s, indicating some ADC variability in the visually rather homogeneous tumour. The small ROI data were not used in the present analysis

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