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Table 1 List of contrast agents applied in this in vitro study

From: The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

Imaging system Chemical name Trade name (manufacturer) Structure, ionicity Initial concentration Osmolality (mOsm/kg H2O) Viscosity (mPa·s, 37 °C) Clearance
MRI Gadobutrol Gadovist (Bayer Vital, Leverkusen, Germany) Macrocyclic, nonionic 1.0 mmol/mL 1603 5.0 Renal
MRI Gadoterate meglumine Dotarem (Guerbet, Roissy, France) Macrocyclic, ionic 0.5 mmol/mL 1350 2.0 Renal
MRI Gadodiamide Omniscan (General Electric Healthcare Buchler, Braunschweig Germany) Linear, nonionic 0.5 mmol/mL 780 1.4 Renal
MRI Gadopentetate dimeglumine Magnograf (Jenapharm, Jena, Germany) Linear, ionic 0.5 mmol/mL 1960 2.9 Renal
MRI Gadoxetate Primovist (Bayer Pharma, Berlin, Germany) Linear, ionic 0.25 mmol/mL 688 1.2 50% hepatic, 50% renal
CT Iomeprol Imeron 300 M (Bracco Imaging, Konstanz, Germany) Monomeric, nonionic 300 mg iodine/mL 521 2.9 Renal
CT Iopromide Ultravist 300 (Bayer Vital, Leverkusen, Germany) Monomeric, nonionic 300 mg iodine/mL 590 4.7 Renal
  1. MRI magnetic resonance imaging, CT computed tomography