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European Radiology Experimental

Table 3 Dimensionless DTI parameters of in vivo and ex vivo regions of interest using the surface coil and one excitation

From: Impact of fixation, coil, and number of excitations on diffusion tensor imaging of rat brains at 7.0 T

Structures

Dimensionless parameters

In vivo

Ex vivo

p value

Corpus callosum

Fractional anisotropy

0.45 ± 0.05

0.55 ± 0.02

0.010

R1 (λ2/λ1)

0.64 ± 0.04

0.52 ± 0.12

0.076 (ns)

R2 (λ3/λ1)

0.37 ± 0.06

0.27 ± 0.03

0.020

R3 (λ2/λ3)

1.76 ± 0.18

2.22 ± 0.33

0.057 (ns)

External capsule

Fractional anisotropy

0.42 ± 0.01

0.42 ± 0.02

0.555 (ns)

R1 (λ2/λ1)

0.59 ± 0.09

0.69 ± 0.02

0.060 (ns)

R2 (λ3/λ1)

0.4 ± 0.02

0.41 ± 0.02

0.530 (ns)

R3 (λ2/λ3)

1.61 ± 0.12

1.7 ± 0.07

0.279 (ns)

Anterior commissure

Fractional anisotropy

0.48 ± 0.02

0.50 ± 0.08

0.550 (ns)

R1 (λ2/λ1)

0.5 ± 0.02

0.63 ± 0.58

0.004

R2 (λ3/λ1)

0.38 ± 0.02

0.33 ± 0.09

0.184

R3 (λ2/λ3)

1.33 ± 0.08

1.85 ± 0.45

0.052 (ns)

Internal capsule and cerebral peduncle

Fractional anisotropy

0.62 ± 0.04

0.62 ± 0.02

1.000 (ns)

R1 (λ2/λ1)

0.38 ± 0.04

0.51 ± 0.03

0.004

R2 (λ3/λ1)

0.26 ± 0.03

0.21 ± 0.02

0.028

R3 (λ2/λ3)

1.47 ± 0.04

2.6 ± 0.25

< 0.001

Optic tract

Fractional anisotropy

0.61 ± 0.04

0.63 ± 0.05

0.641 (ns)

R1 (λ2/λ1)

0.39 ± 0.03

0.47 ± 0.04

0.013

R2 (λ3/λ1)

0.27 ± 0.05

0.22 ± 0.05

0.204 (ns)

R3 (λ2/λ3)

1.46 ± 0.17

2.37 ± 0.51

0.018

Cortex

Fractional anisotropy

0.22 ± 0.07

0.25 ± 0.03

0.436 (ns)

R1 (λ2/λ1)

0.79 ± 0.09

0.79 ± 0.02

0.897 (ns)

R2 (λ3/λ1)

0.66 ± 0.09

0.61 ± 0.04

0.322 (ns)

R3 (λ2/λ3)

1.20 ± 0.04

1.30 ± 0.06

0.035

Hippocampus

Fractional anisotropy

0.18 ± 0.05

0.23 ± 0.29

0.125 (ns)

R1 (λ2/λ1)

0.83 ± 0.07

0.8 ± 0.02

0.455 (ns)

R2 (λ3/λ1)

0.7 ± 0.06

0.62 ± 0.04

0.087 (ns)

R3 (λ2/λ3)

1.18 ± 0.17

1.29 ± 0.04

0.002

Striatum

Fractional anisotropy

0.27 ± 0.03

0.3 ± 0.06

0.320 (ns)

R1 (λ2/λ1)

0.72 ± 0.04

0.75 ± 0.04

0.259 (ns)

R2 (λ3/λ1)

0.61 ± 0.03

0.55 ± 0.07

0.191 (ns)

R3 (λ2/λ3)

1.18 ± 0.02

1.39 ± 0.11

0.006

  1. Data are presented as mean ± standard deviation (× 10−4 mm2/s)
  2. DTI diffusion tensor imaging, ns not significant
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