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Table 3 Dimensionless DTI parameters of in vivo and ex vivo regions of interest using the surface coil and one excitation

From: Impact of fixation, coil, and number of excitations on diffusion tensor imaging of rat brains at 7.0 T

Structures Dimensionless parameters In vivo Ex vivo p value
Corpus callosum Fractional anisotropy 0.45 ± 0.05 0.55 ± 0.02 0.010
R1 (λ2/λ1) 0.64 ± 0.04 0.52 ± 0.12 0.076 (ns)
R2 (λ3/λ1) 0.37 ± 0.06 0.27 ± 0.03 0.020
R3 (λ2/λ3) 1.76 ± 0.18 2.22 ± 0.33 0.057 (ns)
External capsule Fractional anisotropy 0.42 ± 0.01 0.42 ± 0.02 0.555 (ns)
R1 (λ2/λ1) 0.59 ± 0.09 0.69 ± 0.02 0.060 (ns)
R2 (λ3/λ1) 0.4 ± 0.02 0.41 ± 0.02 0.530 (ns)
R3 (λ2/λ3) 1.61 ± 0.12 1.7 ± 0.07 0.279 (ns)
Anterior commissure Fractional anisotropy 0.48 ± 0.02 0.50 ± 0.08 0.550 (ns)
R1 (λ2/λ1) 0.5 ± 0.02 0.63 ± 0.58 0.004
R2 (λ3/λ1) 0.38 ± 0.02 0.33 ± 0.09 0.184
R3 (λ2/λ3) 1.33 ± 0.08 1.85 ± 0.45 0.052 (ns)
Internal capsule and cerebral peduncle Fractional anisotropy 0.62 ± 0.04 0.62 ± 0.02 1.000 (ns)
R1 (λ2/λ1) 0.38 ± 0.04 0.51 ± 0.03 0.004
R2 (λ3/λ1) 0.26 ± 0.03 0.21 ± 0.02 0.028
R3 (λ2/λ3) 1.47 ± 0.04 2.6 ± 0.25 < 0.001
Optic tract Fractional anisotropy 0.61 ± 0.04 0.63 ± 0.05 0.641 (ns)
R1 (λ2/λ1) 0.39 ± 0.03 0.47 ± 0.04 0.013
R2 (λ3/λ1) 0.27 ± 0.05 0.22 ± 0.05 0.204 (ns)
R3 (λ2/λ3) 1.46 ± 0.17 2.37 ± 0.51 0.018
Cortex Fractional anisotropy 0.22 ± 0.07 0.25 ± 0.03 0.436 (ns)
R1 (λ2/λ1) 0.79 ± 0.09 0.79 ± 0.02 0.897 (ns)
R2 (λ3/λ1) 0.66 ± 0.09 0.61 ± 0.04 0.322 (ns)
R3 (λ2/λ3) 1.20 ± 0.04 1.30 ± 0.06 0.035
Hippocampus Fractional anisotropy 0.18 ± 0.05 0.23 ± 0.29 0.125 (ns)
R1 (λ2/λ1) 0.83 ± 0.07 0.8 ± 0.02 0.455 (ns)
R2 (λ3/λ1) 0.7 ± 0.06 0.62 ± 0.04 0.087 (ns)
R3 (λ2/λ3) 1.18 ± 0.17 1.29 ± 0.04 0.002
Striatum Fractional anisotropy 0.27 ± 0.03 0.3 ± 0.06 0.320 (ns)
R1 (λ2/λ1) 0.72 ± 0.04 0.75 ± 0.04 0.259 (ns)
R2 (λ3/λ1) 0.61 ± 0.03 0.55 ± 0.07 0.191 (ns)
R3 (λ2/λ3) 1.18 ± 0.02 1.39 ± 0.11 0.006
  1. Data are presented as mean ± standard deviation (× 10−4 mm2/s)
  2. DTI diffusion tensor imaging, ns not significant