Fig. 1From: Estimated intracranial volume from FreeSurfer is biased by total brain volumeIllustration of FreeSurfer atlas alignment for estimation of intracranial volume. a T1-weighted image of a participant with frontal lobe dementia. b MNI305 atlas aligned to the T1-weighted image. c T1-weighted image with the aligned atlas overlaid and the intracranial surface of the atlas delineated (pink). d T1-weighted image with the brain surface (blue contour), the intracranial surface of the atlas (pink), and the actual intracranial surface (green) delineated; the atlas surface (pink) seems to follow an outer perimeter set by the gyri rather than following the intracranial surface (green)Back to article page