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Table 1 Applied acoustic power and energy, estimated thermal dose volume (V240EM), and maximum recorded tissue temperature for 27 separate sonications using from 2 mm to 12 mm diameter cells for exposure durations ranging from 16 to 36 s in ex-vivo lamb legs (n = 6)

From: Value of diffusion-weighted imaging for monitoring tissue change during magnetic resonance-guided high-intensity focused ultrasound therapy in bone applications: an ex-vivo study

Cell diameter/exposure duration

Power (W)

Energy (kJ)

V240EM (cm3)

Maximum temperature (°C)

2 mm/16 s

90

1.44

0.83

81.2

120

1.92

2.63

67.2

150

2.40

3.06

94.9

190

3.04

3.57

112.4

190

3.04

2.87

101.4

4 mm/16 s

20

0.32

0.00

42.1

40

0.64

0.15

61.7

60

0.96

0.16

67.2

80

1.28

0.65

71.6

120

1.92

0.74

77.1

150

2.40

4.10

92.6

160

2.56

2.28

113.6

190

3.04

2.59

98.9

190

3.04

4.12

113.2

8 mm/20 s

20

0.40

0.03

62.5

40

0.80

0.39

58.8

40

0.80

0.61

54.6

60

1.20

1.16

69.1

80

1.60

0.90

68.8

120

2.40

3.36

77.1

150

3.00

5.14

78.7

150

3.00

4.38

81.8

12 mm/36 s

20

0.72

0.21

59.7

40

1.44

2.72

89.9

60

2.16

3.92

74.1

80

2.88

5.46

81.2

80

2.88

5.75

81.1

  1. In each case, the highest power exposure was delivered in two different samples