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European Radiology Experimental
Fig. 1 | European Radiology Experimental

Fig. 1

From: Simultaneous dual-contrast multi-phase liver imaging using spectral photon-counting computed tomography: a proof-of-concept study

Fig. 1

Injection protocol and timing characteristics for dual-contrast agent enhanced multi-phase SPCCT of the liver. The portal venous phase is reached within T3 (~70 s) following CA injection in humans, whereas the exact time point of arterial distribution (T1–T0) depends on the individual patient blood flow. For dual-contrast SPCCT imaging, synchronised portal venous distribution of CA1 and arterial distribution of CA2 at one time point is necessary (= T3). The sequence is started at T0, where CA1 is injected. At T3, CA1 shows a portal venous distribution. The time period T1–T0 defines the time necessary for enhancement in arterial phase. Then, CA2 is injected at T2 to assure arterial phase of CA2 at T3. At T3, the SPCCT scan is performed, with an arterial distribution of CA2 and a portal venous contrast of CA1. Blue dotted line, arterial distribution of CA1; blue line, portal venous distribution of CA1; red line, arterial distribution of CA2

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