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European Radiology Experimental
Fig. 3 | European Radiology Experimental

Fig. 3

From: Precision of manual two-dimensional segmentations of lung and liver metastases and its impact on tumour response assessment using RECIST 1.1

Fig. 3

The 95% confidence intervals (95% CIs) obtained for the limits of RECIST 1.1 criteria of stable disease, progressive disease (PD), and partial response (PR) using diameter. In the lung, it appeared that standard deviation decreased as diameter or area of the segmented tumour increased. The opposite was observed in the liver. a The 95% CI of the stable disease (y = x) in the lung did not cross the calculated 95% CI of the lower bound of PD (y = 1.2x). b The 95% CI of the stable disease in the lung did not cross the calculated 95% CI of the upper bound of PR (y = 0.7x). c The 95% CI of the stable disease in liver shows an overlap (blue zone) with 95% CI of the lower bound of PD. The cut-off value was x1 = 22.7 mm (dashed line). d The 95% CI of the stable disease in the liver did cross the calculated 95% CI of the upper bound of PR (blue zone). The cut-off value was x2 = 37.9 mm (dashed line)

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