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Table 2 Study results magnetic resonance imaging (MRI) data

From: Noninvasive assessment and quantification of tumour vascularisation using MRI and CT in a tumour model with modifiable angiogenesis – An animal experimental prospective cohort study

  H1299 A549 All tumours
Non-co-transplanted Co-transplanted p value Non-co-transplanted Co-transplanted p value Non-co-transplanted Co-transplanted p value
Tumour volume T2 [cm3] 1.6 (2.4) 3.8 (4.8) 0.001 0.2 (0.3) 4.4 (6.5) 0.000 0.2 (1.7) 4.0 (5.2) <0.001
TOF Numeric scale 1.3 ± 0.1 1.7 ± 0.1 0.009 1.2 ± 0.1 1.4 ± 0.1 0.009 1.2 ± 0.1 1.5 ± 0.1 0.006
Maximal ADCdiff [mm2/s × 10−6] 1473 (616) 1672 (597) 0.047 1206 (396) 1714 (674) 0.005 1320 (441) 1695 (546) <0.001
Minimal ADCdiff [mm2/s × 10−6] 311 (385) 149 (77) <0.001 348 (199) 173 (135) <0.001 346 (224) 166 (97) <0.001
Maximal ADCperf [mm2/s × 10−6] 1712 (830) 2994 (305) <0.001 1612 (614) 2999 (657) <0.001 1616 (661) 2999 (476) <0.001
Mean ADCperf [mm2/s × 10−6] 568 (149) 722 (106) 0.001 646 (262) 723 (184) 0.203 636 (208) 723 (144) 0.005
  1. In vivo MRI quantitative results of T2 volumetry, time-of-flight (TOF) and apparent diffusion coefficient (ADC). First and second column show results separated for both cell lines, third column tumour cell lines merged together. Median (interquartile range); TOF: mean ± SD