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Fig. 3 | European Radiology Experimental

Fig. 3

From: Semi-quantitative evaluation of signal intensity and contrast-enhancement in Modic changes

Fig. 3

Median and 25th and 75th percentiles of NSIPRE (a), NSIDIFF (b) and NSINORM.DIFF (c) for MC type and control ROI in the other vertebra (OV) or in the same vertebra (SV). *p < 0.050, **p < 0.001 indicate whether the population has a median value significantly different with respect to zero. Bars indicate which pairs of MC type are significantly different (Dunn’s method, p < 0.050). NSIPRE is higher than zero (p < 0.001) for MCs II, is lower than zero (p < 0.001) for MCs I and is not statistically different from zero for MCs I/II. MCs I and MCs I/II have a higher NSIDIFF than MCs II, and MCs I and MCs I/II have a median NSIDIFF higher than zero (all cases, p < 0.001), while for MCs II only for SV control was the median value lower than zero (p = 0.029; for OV, p = 0.213). MCs I and MCs I/II have a higher NSINORM.DIFF than MCs II; median NSINORM.DIFF for MCs I/II is lower than MCs I but is not statistically significant. NSINORM.DIFF median values for MCs I and MCs I/II are higher than zero (p < 0.001; but NSINORM.DIFF SV, p = 0.004), while MCs II have median values lower than zero (p < 0.001). DIFF mean difference between post and pre contrast signal intensity, MC Modic change, NORM.DIFF ratio between PRE and DIFF (×100), NSI normalised signal intensity, PRE mean pixels encompassed in the ROI

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