Parameters | sTTS | cTTS | Controls | p-value | |
---|---|---|---|---|---|
Population, n | 19 | 31 | 30 | - | |
Age, years | 67 ± 14 | 63 ± 11 | 60 ± 11 | 0.111 | |
Onset-to-CMR, days | 5.3 ± 2 | 14.2 ± 6 |  −  | 0.001 | |
Phenotype, n (%) | Apical | 11 (58) | 25 (81) |  −  | 0.167 |
Mid | 5 (26) | 3 (10) |  −  | 0.171 | |
Basal | 1 (5) | 1 (3) |  −  | 0.694 | |
Focal | 2 (11) | 2 (7) |  −  | 0.576 | |
lvEF range, n (%) |  < 40% | 3 (16) | 3 (10) |  −  | 0.103 |
40–50% | 6 (32) | 4 (13) |  −  | 0.001 | |
51–60% | 7 (37) | 14 (45) | 8 (26) | 0.323 | |
 > 60% | 3 (16) | 10 (32) | 23 (74) |  < 0.001 | |
lvESV/BSA, mL/m2 | 40.6 ± 18.4 | 34.4 ± 14.1 | 23.9 ± 9.6 | 0.208 | |
lvEDV/BSA, mL/m2 | 76.3 ± 19 | 73.8 ± 15.8 | 65.7 ± 10.6 | 0.634 | |
lvEF, % | 47.4 ± 11.9 | 54.8 ± 9.9 | 63.1 ± 5.9 | 0.028** | |
rvESV/BSA, mL/m2 | 33.3 ± 9.2 | 31 ± 11 | 31 ± 11 | 0.486 | |
rvEDV/BSA, mL/m2 | 70.2 ± 15.4 | 71.2 ± 15.3 | 73 ± 14.7 | 0.832 | |
rvEF, % | 52.7 ± 7.1 | 56.4 ± 9.2 | 58 ± 8.1 | 0.165 | |
laEDV, mL | 63.8 ± 19.8 | 64.9 ± 25.2 | 59.7 ± 18.3 | 0.553 | |
laS_r, % | 18.9 ± 2.7 | 19.5 ± 3 | 24 ± 2.8 |  < 0.001 | |
laS_cd, % | 7 ± 2.6 | 9.5 ± 3.5 | 12.5 ± 2.6 |  < 0.001** | |
laS_bp, % | 12.7 ± 2.6 | 9.8 ± 2 | 9.7 ± 1.9 | 0.001 | |
laSR_r, l/s | 0.8 ± 2 | 0.8 ± 0.3 | 1.2 ± 0.4 |  < 0.001 | |
laSR_cd, l/s (median [iqr]) | -0.7, (-1.2, -0.3) | -0.7, (-1.8, -0.3) | -1.1, (-2.0, -0.6) |  < 0.001 | |
laSR_bp, l/s | -1.1 ± 0.3 | -1 ± 0.3 | -1.3 ± 0.5 | 0.078 | |
laGRS, % | 35.6 ± 11.4 | 36.7 ± 12.3 | 52.8 ± 9.8 | 0.001 | |
lvGRS, % | 23.2 ± 8.5 | 26.1 ± 7.2 | 33.6 ± 8.2 | 0.003 | |
lvGCS, % | -14.5 ± 3.8 | -16 ± 3.3 | -21.8 ± 2.9 |  < 0.001 | |
lvGLS, % | -12.2 ± 3.9 | -14.6 ± 3.8 | -19.7 ± 2.6 |  < 0.001** | |
lvGRSR, l/s | 1.1 ± 0.3 | 1.3 ± 0.3 | 1.6 ± 0.3 | 0.001 | |
lvGCSR, l/s (median [iqr]) | -0.7, (-1.1, -0.4) | -0.8, (-1.26, -0.9) | -1.0, (-1.2, -0.7) |  < 0.001 | |
lvGLSR, l/s | -0.6 ± 0.2 | -0.7 ± 0.2 | -1.2 ± 0.6 |  < 0.001 | |
lvEDEMA, n (%) | 16 (100) | 31 (100) | 0 (0) |  < 0.001 | |
lvLGE, n (%) | 1 (3) | 2 (7) | 0 (0) | 0.369 |